2015 Thesis
Security in the New Era of Synthetic Biology
B.S. Cellular & Molecular Biology · University of Newcastle upon Tyne, UK
Synthetic biology rapidly advanced genetic engineering, yet existing regulatory
frameworks largely rely on inherited existing GMO legislation from the 90's and 00's that was never designed
with Synthetic Biology's unique capabilities in mind.
In the thesis, I examine the legal, security, and social issues created by that gap, including
dual-use research risks, biocontainment challenges, and the intellectual property landscape governing synthetically
modified organisms.
Paradoxically, at the time of writing (2015), the field’s own technical complexity and economic
barriers act as natural constraints on misuse, while open-source platforms like BioBricks simultaneously
accelerate innovation and raise biosecurity concerns.
The thesis concludes that synthetic biology’s most transformative potential lies
in strengthening global food, energy, and health security, from engineering bacteriophages to combat
antibiotic resistance, to producing next-generation biofuels.
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